★★★★★ 5
yes
they're ok
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Reviewed in the United States on April 4, 2026
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Description
Yes there is good evidence that acetaminophen (the active ingredient in Tylenol) can deplete glutathione under certain conditions. But whether that matters depends on dose, duration, and individual factors. Salivary Aldehyde Dehydrogenases in Oral Toxicology: Biological Functions, Disease Associations, and Translational Perspective Reg'Activ Line I Essential Formulas Glutathione an overview ScienceDirect Topics
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4.3 ★★★★★
Based on 460 reviews
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Product Reviews
★★★★★ 1
Cheap, very thin, and weak
They are very cheap and very weak. You need to double and triple up to use them, so it isn't worth it.
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Reviewed in the United States on January 20, 2026
★★★★★ 5
Great retinol face moisturizer
Palmers always makes a great product in my opinion. This one's no different. It's a retinol that doesn't irritate my skin. I use a moisturizer below and on top. It absorbs quickly but doesn't sit on the skin. It's helped with my fine lines quicker than other products I've used and the price point is unmatched. Great product,not a strong scent, will continue to use.
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Reviewed in the United States on January 10, 2026
★★★★★ 5
Very Good
Why did you pick this product vs others?:
I have been using this product for 2 days and can see a difference in the appearance of my skin. 40+ this does help with fine lines. I can already see my smile lines appearing less noticeable. A little goes a long way. You don't need to use a lot, or it will look like clown makeup, and you will have to work it in, but it is not a big deal. Also, if you have sensitive skin, I wouldn't buy a product clearly listed as extra strength. It will work as an extra strength product.
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Reviewed in the United States on July 6, 2025
★★★★★ 4
Works but it takes time
It does work but takes a few months to get results.
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Reviewed in the United States on January 15, 2026